The anti-inflammatory activity of ethanolic stem-bark extract of Boswellia ovalifoliolata was evaluated in experimentally induced acute and chronic inflammation in Wistar rats using carrageenin paw edema (acute) and cotton pellet granuloma (chronic) models of inflammation. The % decrease in paw edema, activites of ALT, AST and acid phosphatase in acute and chronic models, and GGT, liver lipid peroxides and reduced glutathione in chronic model were measured. Erythrocyte membrane stabilization test was conducted and the percent membrane stabilization of RBC was calculated. The test herb and the standard drug diclofenac significantly (P<0.05) reduced the concentration of ALT and AST, GGT, acid phosphatase in serum and lipid peroxides in liver and increased the GSH concentration. The ethanolic extract of B. ovalifoliolata exhibited significant anti-inflammatory activity in acute and chronic models of inflammation.
Loading....